Hyunsun Jo

Hyunsun Jo

Company: Pin Therapeutics

Job title: CEO

Seminars:

Panel Discussion: Demonstrating Degrader Efficacy 4:25 pm

• What is the challenge behind demonstrating degrader efficacy? • What methods are currently followed to overcome the challenge of showing degrader targeting to the protein of interest? • Establishing correlation between ubiquitination and target degradation, in vitro and in cell system remains a challenge. Tackling this problem will be key to establishing structure-activity relationship…Read more

day: Agenda: TPD: Emerging Disease Applications Beyond Oncology

Things to Consider in Degrader Development Using E3 Ligases in Immune Cells 3:10 pm

• Things that control the expression/activity of the E3/E2 system • A target protein that would be good to develop using the differentiated expression/activity of the E3/E2 systemRead more

day: Agenda: TPD: Emerging Disease Applications Beyond Oncology

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